Global SYK Inhibitors Market and Clinical Trials Outlook 2028

  • No. of Pages: 114
  • Publish Date: February-2023
  • Category: Pharmaceutical and Healthcare
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Global SYK Inhibitors Market, Drug Price, Sales and Clinical Trials Outlook 2028 Report Highlights:


  • Global SYK Inhibitors Market Current and Forecast Sales
  • Global SYK Inhibitors Market Opportunity: > USD 300 Million
  • SYK Inhibitors Clinical Trials By Company, Country, Indication and Phase
  • Approved SYK Inhibitor Drug In market: 1 Drug (Fostamatinib)
  • Dosage, Patent, Price and Sales Insight On Fostamatinib
  •  Competitive Landscape


With recent significant advances in the field of immunotherapy, determination of several novel therapeutic approaches for multiple different forms of disorders often remains a challenge. One such novel target that is emerging to have some possible promising potential for drug development in several disorders including cancers is SYK. Spleen tyrosine kinase (SYK) is cytoplasmic non-receptor kinase which is known to have oncogenic properties and since has been extensively investigated into. Its therapeutic potential has been noticed by pharmaceutical companies and drugs against SYK have started their initial clinical trial phases.


Spleen tyrosine kinase (SYK) plays an essential role in regulating immune inflammatory responses by activating a variety of downstream signaling pathways involved in the pathogenesis of several diseases. Several pharmaceutical companies have started to explore the therapeutic possibility of SYK inhibitors and government officials have been encouraging these research and development activities so as to develop more domestically produced drug candidates and attract foreign multinationals in their respective country by offering clinical benefits. Grifols which is a leading global healthcare company has announced that its SYK inhibitor, Tavlesse is now available across the United Kingdom for adult patients with chronic ITP.


Tavlesse (Fostamatinib) is the first and only SYK inhibitor that is indicated for adult patients with chronic immune thrombocytopenia (ITP) who have not responded to previous treatments. The drug has now been recommended by UK’s National Institute for Health and Care excellence (NICE). It is the only targeting agent that works by protecting platelets from destruction. Grifols has exclusive rights for Fostamatinib in Europe, Turkey, Middle East, North Africa and CIS countries thanks to the licensing agreement collaboration reached with US based Rigel Pharmaceuticals.


The spleen tyrosine kinase is involved in variety of biological activities which has led to robust research and development being done on making a robust clinical pipeline for the future drug candidates. Factors like rising investments and increasing funds for research and development activities, increasing prevalence of disorders, surging partnerships among pharmaceutical companies and the advancement in medical technology are fueling the market opportunity for spleen tyrosine kinase (SYK) inhibitors resulting in flouring market growth.


This emerging target has resulted in several pharmaceutical industries trying to develop novel therapies and testing them under clinical trials. Recently, Hutchmed Limited announced that it has completed patient enrollment for a pivotal phase II clinical trial for its drug candidate Sovleplenib for the treatment of adult patients with primary immune thrombocytopenia (ITP) in China. The topline results from the study, ESLIM-01 are expected to be reported during the second half of 2023. If the trial shows the expected success, the company would progress for marketing authorization by the China National Medical Products Administration (NMPA). Sovleplenib is a novel investigational selective molecule inhibitor for oral administration that targets SYK inhibition.


The market reach of spleen tyrosine kinase inhibitors is very diverse and broad due to every country wanting to develop novel therapeutics for the target. The high demand for the therapy with developed healthcare infrastructure and benefiting government policies will be determining which region moves the farthest in the spleen tyrosine kinase inhibitor market. The increased adoption towards new approaches, large population and innovative product launches are additional factors that determine the window of opportunity for key market players. This report contains a thorough analysis of the recent trend and shifts towards SYK inhibitors and provides detailed information about the possible opportunities that have opened up since the introduction of SYK inhibitors in the market.

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