Whole-Brain Radiation Therapy Vs. Stereotactic Radiosurgery Analysis for Brain Metastasis

Release Date: 12-Aug-2020

Brain metastasis is one of the most important concern in the oncology research world. In order to conquer more information, a group of researchers at The Ohio State University conducted 2 research clinical trials that were randomized. The primary aim of the 2 clinical trials were to compare the clinical outcomes of stereotactic radiosurgery and whole-brain radiation therapy (WBRT) in the patients suffering from brain metastases. It was oriented towards comparing the quality of the life when treated with the therapies alone. 


Patients of brain metastases have not been able to receive complete treatment healthcare because of aggressive radiation treatments. In general, treatment of the patients suffering from brain metastasis with radiation only treated tumor cells to some extent and majorly impacted the quality of life of the patients. Therefore, the main goal of the researchers was to develop a radiation treatment that not only can improve the systemic regulation but also improve the quality of the life of the patients suffering from brain metastases.


In order to do so, two therapies i.e. WBRT and stereotactic radiosurgery were two therapies that were expected to deliver some potential outcomes for the patients suffering from brain metastases. The clinical results of the same showed that the patients who received WBRT represented a 2-year trend towards increased cognitive decline in 5 out of 6 measures. Also, the patients who received stereotactic radiosurgery only showed 2 out of 6 cognitive measures. As both the therapies showed a decline in the recall and recognition. The overall results showed that stereotactic radiosurgery was more potential therapy when compared with WBRT arm.

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