Microrobots to make Therapeutic Challenges with Treating Colon Disease to Decline
Release Date: 12-Nov-2020
A novel micromachine developed by the researchers from Purdue University are on the edge of revolutionizing the targeted drug delivery system to the colon. Colon among all the parts of the body provides an easy introduction of the drug and high chance of proving the small-but-mighty machine to deploy the drugs at the desired drugs. The connection of the microrobots with spinning magnetic field is also believed to make the robots deliver promising results in case of colon diseases.
The polymer coating of the microrobots is also leading the robots to limit off-targeting till the robots reached the desired location i.e. the target site. The researchers working on the clinical research study have already piloted the microrobots on the colons of the mice. The researchers used saline solution for the insertion of the microrobots into the rectum of the animals. They also observed the movement of the machine in real time using the technology of ultrasound. The introduction of the drug with the help of microrobots led to the dispersion of the drug over the course of an hour.
The researchers in order to make the clinical study work efficiently in the humans requires dozens of microrobots so that multiple target sites could be targeted with the help of multiple drug payloads. It is also observed by the researchers that the introduction of microrobots with the drug will also reduce adverse toxicities when compared with the old and traditional drugs used to. From the diagnostic perspective, this clinical research study is estimated to deliver promising results in declining the mortality rate of the patients suffering from any kind of colon diseases.
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