Release Date: 12-Jul-2024
Bispecific antibodies exert their therapeutic effects through intricate mechanisms of action. By engaging two distinct targets, they can bridge immune cells to tumors, such as T cells to cancer cells, facilitating tumor cell killing. Additionally, they can block two different signaling pathways simultaneously, leading to enhanced efficacy compared to monospecific antibodies. Some bispecific antibodies also function by cross-linking immune cells, triggering potential immune responses against tumors. Furthermore, they can neutralize soluble factors or target multiple diseases pathways simultaneously. Such multifaceted mechanisms make bispecific antibodies versatile tools in the treatment of various diseases, offering novel approaches to combating complex pathological processes.
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