Atara Biotherapeutics Received Approval for Clinical Phase 1 Clinical Trial for CAR-T Cell Therapy for Mesothelioma Patients

Release Date: 17-Nov-2020

Recently, Atara Biotherapeutics received the approval for phase 1 clinical trial of their CAR-T cell therapy for solid tumors such as mesothelioma by the US FDA. The clinical trial focused by the researchers from Atara Biotherapeutics is a next-generation clinical research study i.e. ATA2271. The clinical trial for CAR-T cell therapy is estimated to harness two different types of immunotherapies. It will also include some more beneficial modifications to the available CAR-T cell therapy. The researchers are focused towards enhancing the survival as well as function of the CAR-T cell therapy as well as addition of PD-1 checkpoint inhibitor to the CAR-T cells.

The first modification that is entitled in the clinical trial will focus on enabling the CAR-T cell to survive for longer time period. It is estimated by the researchers that two important modifications in the CAR-T cell therapy will lead to more efficient results against different types of cancers. It is also believed that the patients suffering from mesothelioma could be able to experience reduction in the size of the tumor and very less chance of cancer recurrence.

The researchers focused towards the clinical research study is inclined towards treating variety of cancer types. It is believed by the researchers that the arrival of novel treatment for mesothelioma will completely transform the quality of the life of the patients who have been suffering from cancer for prolonged period of time. Although the respective clinical trial hasn’t been yet studied by the researchers on the humans but the pre-clinical insights received is estimated to provide deeper insight towards the efficiency of CAR-T cell therapy in case of mesothelioma patients.